How To Ship Enbrel Safely To Your Door

Ship Enbrel Safely and Enbrel boxes

Enbrel (etanercept) is a medication that is commonly used to treat certain autoimmune conditions, such as rheumatoid arthritis and psoriasis. It is important to ship and store Enbrel properly to maintain its effectiveness and safety.

Shipping medication, especially prescription medications like Enbrel, from a Canadian online pharmacy to the USA requires careful consideration of the legal and safety requirements.  When deciding to purchase Enbrel (etanercept) form a pharmacy in Canada, always ensure the pharmacy is licensed in the jurisdiction they are located in.  Enbrel should only be purchased from a reputable and licensed Canada online pharmacy.  This will ensure your Enbrel from Canada is genuine and properly stored.


Your Canadian online pharmacy should require some very standard items before they agree to fill your prescription:

  • Obtain a Valid Prescription: Ensure you have a valid prescription for Enbrel from a licensed healthcare provider. This prescription should be in your name and up-to-date.
  • Secured Packaging: Keep the medication in its original packaging, including the manufacturer’s packaging, if possible. If not, use tamper-evident packaging to ensure the integrity of the medication.
  • US Customs clearance: Your package may be subject to customs inspection prior to crossing into the USA.  Contents are declared on the package shipping label and normally there are no issues with prescription medications being sent into the USA.  Your online pharmacy will have experience with this and will be able to provide guidance should your product be held at customs. 


  • Reliable Shipping Carrier: Choose a reputable shipping carrier that offers tracked international shipping services. Medications being shipped from a Canadian drugstore or pharmacy should be shipped using the fastest service Canada Post has to offer.  Canada Post hands the package off to the US Postal Service for quick delivery to your door. 
  • Track the Shipment: Use the tracking number provided by your online pharmacy to monitor the progress of your shipment.
  • Engineered Thermal Boxes: Regular polystyrene (Styrofoam®) thermal packaging may not be enough.  Engineered thermal boxes are much more robust at maintaining temperature.
  • Temperature Data Loggers: Data loggers are included in the engineered thermal boxes to measure temperature and provide proof to the patient and the Canadian pharmacist that your Enbrel has arrived safely and the cold chain has not been broken.

For more information on safely shipping Enbrel from Canada, please have a read through this article:


When your tracked and engineered thermal box arrives at your door, be sure to receive it, open it, and place your product in the fridge immediately according to the pharmacy’s recommendations. 

Next, check the datalogger. 

  • If your data logger is flashing green only, perfect. Your product is in your fridge and as safe to use.  
  • If the data logger is flashing red at all, follow the instructions that are included in the package. Your pharmacy will have access to the data and can provide guidance on whether your product is safe to use.


Here are the typical refrigeration requirements for Enbrel:

  • Enbrel should be stored in the refrigerator at a temperature between 36°F and 46°F (2°C to 8°C). It is important to keep it within this temperature range to prevent degradation of the medication. Do not freeze Enbrel as this can damage the medication and make it ineffective.  Protect from light.
  • It is a good practice to keep Enbrel in its original packaging, including the carton and any protective materials provided by the manufacturer. This also protects the product from light.
  • Always check the expiration date on the Enbrel packaging before using it. Do not use Enbrel if it has expired.
  • If you need to travel with Enbrel and refrigeration is not readily available, you can use a travel cooler pack specifically designed for medications. Follow the manufacturer’s instructions for using these packs to maintain the proper temperature.

If you have any questions or concerns about the storage or handling of Enbrel, it is advisable to consult your healthcare provider or pharmacist for guidance.

Always follow the specific storage instructions provided by the manufacturer of your Enbrel product, as there may be slight variations in packaging and storage recommendations. Proper storage is essential to ensure the medication’s safety and effectiveness in managing your medical condition.

Please note that regulations and procedures may change over time, so it’s crucial to verify the current requirements with the FDA, your Canadian online pharmacy, and the shipping carrier before attempting to ship Enbrel or any prescription medication across borders. Additionally, consider consulting with a customs broker or legal expert who specializes in pharmaceutical imports for personalized guidance.


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