Coumadin Brand is Being Discontinued – Generic Warfarin is Still Available

Bristol-Myers Squibb announced that the sale and distribution of all strengths of Coumadin (Warfarin Sodium) tablets will be discontinued in the United States, Canada, Latin America, and Saudi Arabia, due to an unexpected manufacturing issue. It will begin on June 1, 2020 . Original source: https://www.bms.com/assets/bms/ca/documents/productmonograph/CANADA-Coumadin-deletion_D-HCP-Communication_FINAL_EN_04.23.2020.pdf


COUMADIN (warfarin sodium) is a prescription medication that interferes with normal blood clotting (coagulation). It is also called an anticoagulant. 

Millions of people depend on anticoagulants – also known as “blood thinners” – to prevent life-threatening blood clots. While these medications do not actually “thin” the blood, they do slow the body’s ability to form dangerous blood clots, such as blood clots in the arms or legs (deep vein thrombosis or DVT) and blood clots in the lungs (pulmonary embolism or PE).


Stopping blood thinners can increase your risk for blood clots, due to the underlying risk factor(s) for which your blood thinner was originally prescribed. These bleeding and clotting risks can be complicated for your healthcare providers to manage.

For patients currently using Coumadin® (warfarin sodium) tablets, healthcare providers will be required to consider alternatives. Prescribing an alternate product is the clinical decision of the healthcare professional in consultation with the patient.

The generic version of Coumadin® is one option. Even though generic warfarin and brand name Coumadin® are considered interchangeable, your health care provider may want you to have your levels checked when making a change like this.  Therefore, it is important to have this discussion with your healthcare team.

In Canada, therapeutic alternatives, including generics, are available. Please check the following information.

Generic Product

Brand name in the US: Coumadin

Generic name: Warfarin Sodium

Product of Canada – Manufactured by various generic manufacturers

Strengths: 1mg, 2mg, 2.5mg, 3mg, 4mg, 5mg, 6mg, 7mg, 7.5mg, 10mg

Dosage form: Tablet

This article is sponsored by CheapoMeds. If you have questions about your prescription medications or any other medication, please contact our team at CheapoMeds by calling toll free 1-844-4CHEAPO (424-3276). One of our patient representatives will be happy to assist you or transfer you to a licensed Canadian pharmacist for a free consultation.

This article contains medical information provided to help you better understand this particular medical condition or process, and may contain information about medication often used as part of a treatment plan prescribed by a doctor.  It is not intended to be used as either a diagnosis or recommendation for treatment of your particular medical situation.  If you are unwell, concerned about your physical or mental state, or are experiencing symptoms you should speak with your doctor or primary health care provider. If you are in medical distress please contact emergency services (such as 911).

Reference:

  • bms.com
  • stoptheclot.org

55 Comments

  1. Due to an unexpected manufacturing issue that cannot be resolved Coumadin is no longer available. Seriously?!?!?!?! Is profitability more important than someone’s life who is dependent upon Coumadin? Apparently so.

    • Thank you for your feedback. Although it can be frustrating for some to find out that brand name Coumadin is being discontinued, the generic version of Coumadin (warfarin) is and has been available in Canada for many years. As the article states, there are alternatives that may work for you. This article was posted to create awareness and to encourage people to engage their physicians with this information. We recommend you have a discussion with your physician regarding any changes that may be possible considering Coumadin brand name is being discontinued

      • This is horrific!!! The generic cause more INR instability thus requiring more lab tests. The US drug companies are greedy monsters!

        • Warfarin sodium is MUCH cheaper. I have been taking Coumadin for years…it is now $270.00 for a 90 day supply. Warfarin is $6 for 90 days supply..
          I do my own INR on a little machine provided thru ny cardiologist office..
          I do agree that the pharmaceutical companies are greedy monsters.

        • I agree. This is the reason I take Coumadin because Warfarin causes my INR to go dangerously high in a short period of time…

        • I have the same problem with INR instability using warfarin. While the Coumadin did cost more it did a much better job controlling my INR. After doing battle with my insurance company and getting them to approve Coumadin the manufacture “quits” making the drug.

      • Generic warfarin is NOT the same! It is made up of different binders that do interfere with its blood thinning capabilities. Also current investigations into Generic medications coming out of China have revealed high levels of known carcinogen has been a constant finding in generic medications. Many people have died from cancer caused by there generic medications including the generic form of valsartin known to have killed over 500,000 people as an investigation this year revealed. Also investigators learned that too often the key ingredients of these generic medications were not measured correctly. With a blood thinner it’s critical that a 4 mg tablet only have 4 mg of its main ingredient. What is happening is that people who take generic warfarin have a difficult time keeping the INR LEVELS ACCURATE! Example one week I would be at a 2.5 INR the following with the exact same dose my INR was at 7.5 a deadly level as internal organs began to bleed out. Other times the levels would bounce the opposite direction and my INR would drop to 1.0 basically non existent blood thinning and I had to deal with life threatening DVT BLOOD CLOTS.
        Absolutely this is an outrage for a manufacture to be so careless in regards to a life saving medication that for many who can not take the new series of daily blood thinning medications out now because those thin on the wrong playlet levels for people with FULL HETEROZYGOUS FACTOR V LEIDEN blood clotting disorder. I will be finding alternative brands for any other medications I currently take that are made by this clown manufacturer as I will not give them another dime of bussiness in my name!

        • Allergic reaction to Warfarin. Been taking 10 months. Blood clotting in good range but my arms and legs itch..always. can get no relief. Does anyone else same issue,

          • Yes, my father has allergic itch to generic warfarin. We need to find the generic that will be best! I encourage all to be proactive with the name of a US-based generic manufacturer of warfarin that has been well-tolerated, safe and effective – as close to branded Coumadin as possible.

          • My God yes. I felt terrible like sand running thru my veins. I gained 35 lbs in a very short time that I have been blessed with for years. I also have factor v blood. Warfarin is not the same as Coumadin. Now with it’s discontinuation what do we do? I am looking at jantoven but it has the same dyes as warfarin. I was looking at the 10 mg that has no dye. This may be a possibility to cut the pill. Checking on this now.

        • My guess is their manufacturing issue is that that were making it in China as that is where one of their large facilities is located. Agree with you on Warfarin issues as my wife was non therapeutic on Warfarin and has to watch numbers closely. This is why all drug manufacturing should be brought back to USA as currently 90% + of all medications are made overseas. Trump has vowed to bring them back to USA

          • My guess is their manufacturing issue is that they were making it in China as that is where one of their large facilities is located. Agree with you on Warfarin issues as my wife was non therapeutic on Warfarin and has to watch numbers closely. This is why all drug manufacturing should be brought back to USA as currently 90% + of all medications are made overseas. Trump has vowed to bring them back to USA

        • Even though Coumadin has been discontinued in the US, Canada, Latin America and Saudi Arabia, it is still available in various other countries. CanadaOnlineHealth.com offers brand name Coumadin 1mg, 2mg, and 5mg, manufactured by Sigma Pharma from New Zealand. (Sigma Pharma acquired Coumadin from Bristol Myers Squibb)

      • If warfarin kept the inr, the value patients are expected to achieve, then there would be no problem. But warfarin DOES NOT keep the inr steady as does Coumadin. Instead it is a CONSTANT BATTLE with adding different doses and multiple weekly blood draws to keep the inr steady.
        Looks like the old machines busted down and the new ones wouldn’t benefit you profitability-wise is all I can guess, based on your “statement”.

    • Really this is a real blow to me as I have been on coumadin (jantoven) for 28 years for a mechanical heart valve. It is the only drug that keeps my INR stable. Have you really done research on this.you are putting many people’s lives in jeopardy.

    • My wife has the same problem except she found out yesterday, 9/9/2020 and ahs been on Coumadin for 30 plus years, Bristol Meyer Squibb does not care at all about people like us
      never have / never will we are on our own!!!!

  2. All about money. They want people to switch to Eliquis which is $500/month. What manufacturing issue could cause them to discontinue manufacturing of a drug they’ve been making for decades? They should give more details if it’s not. Still available all over Europe. Pitiful. Brand Name Coumadin shows better INR control in some individuals. This will have a potentially damaging impact on those people.

    • It is all about money. I have tried other drugs and all have failed.
      Coumadin is literally keeping me alive. Until it directly impacts them they will never understand. Manufacturers could care less about anything other than money.

    • Eliquis and others like this do not work for people who have FACTOR V LEIDEN as it thins on the wrong playlet level. So there is no viable option for people this seemingly rare blood disorder. Those with both genes are that much more at risk. 3000 times more likely to throw a DVT BLOOD CLOT then the normal person.

      • that is what i have Factor V leiden deficiency. I also have a friend who is taking Eliquis who has nose bleeds who they are trying to work with . .

    • I have been on it for 28 yrs as of this past january for mechanical valve. Last 3 with generic and my INRS are all over the place!!!! Every 2 weeks end up increasing or decreasing by 2&1/2 mg. This is ridiculous!!

  3. I would like to know if the decision to discontinue Coumadin is based upon a safety factor or if it no longer cost effective
    for Bristol Meter to produce ir. Generics may have the same main ingredient as the name Brand but the binding factors can be different for each company producing the generic and therefore be absorbed in different parts of the GI tract therefore provide varying dosage absorption. This can result in varying dose absorption. Unfortunately larger companies dispensing pharmaceuticals, each time they purchase a drug, Generally purchase from the cheapest source. So, there is no guarantee that you are receiving the same dosage being absorbed in your body regardless of the dose identified on the bottle.

  4. I have been on both the generic and Coumadin. Coumadin works for me. I have Factor Five and have had many blood clots. This is an awful blow for me. The new meds, the expensive ones, make me very ill.

    • Carol this is a blow to me also. I cannot take generic only the name brand. I have Factor V and a protein C problem. I also have a inferior vena cava obstruction so coumadin has saved my life. I am going to talk with my hematologist this week. They dont want to put me on those other drugs. I feel bad for you

      • Generic warfarin is dangerous for those with factor V.. because the manufacturers are not FDA regulated. The tablets do not have the correct dose of warfarin I’m them. So keeping an even INR is impossible . I had DVTs and a pulmonary Embolism on generic warfarin. I also had a critical high INR that caused my kidney to bleed out. All I’m the same dose the whole time. Finally a doctor at UCSD told me about the problems with the binders put in generic warfarin causing trouble with the metabolism of warfarin and irregular INR. Since then the CHINESE GENERIC PHARMACEUTICALS ARE CURRENTLY UNDER INVESTIGATION FOR NOT PUTTING THE CORRECT DOSAGE OF MEDICINES IN MOST ALL THE GENERICS THEY MAKE. Making drugs like blood thinners dangerous to take as well as blood pressure medicines killing people because they were in to high of a dose or too low because the generic tablets don’t have consistent doses of the main drug in them. Also look up generic Valsartin you will see a current lawsuit and investigations for deaths caused by stage four lung cancer in patients because they put known carcinogens in the drugs they have been selling to America. Why our insurance companies are still insisting we take generic over name brand is amazing. They are not without fault or negligence because they all know the FDA DOES NOT REGULATE GENERIC DRUG MANUFACTURERS LIKE THEY DO NAME BRAND MANUFACTURERS. This known negligence will get these insurance companies sued in the deaths caused by these generic drugs. 500,000 cancer deaths are now known to be connected to Generic Valsartin blood pressure medicine. That’s just the beginning. CHINA MANUFACTURERS MOST ALL OF THE UNITED STATES GENERIC PHARMACEUTICALS!
        Beware !

  5. As a former pharmacist, and now retired pulmonary critical care physician I am most disappointed. I had an aortic valve replacement in 2006. My INR’s were quite variable with generic Warfarin, but stable with Trade name Coumadin – 4 mg daily. I was willing to pay the difference for the stability provided by Coumadin. I am most disappointed to learn Coumadin is being discontinued.

  6. my mom been on Coumadin for 12 years. This really sad how the Bristol-Myers care more for money. Then human life my mom has try Warfarin. Her blood will be a fine one month then the next month all over the place. Her doctor told her is cause Warfarin is made by different companies. He changed her to the Brand name and it help. The time we living there is no compassion. Come go Bristol-Myers please you guys are playing with human life.

  7. This is horrific!! My 99 year old mother who is very sensitive to medications is on Coumadin. Trying to find the next drug suitable for her will be trial and error not a risk we want to take!!!
    We were having some questions that only the manufacture would know they kept referring me to ask the pharmacist. This call was in March or April we had heard that it was being discontinued but she denied that would happen. Well here we are……

  8. My husband was on Coumadin for years. Then when he changed jobs they required him to take generic drugs and his INR went all over the place. We could not get it under control! His doctor requested that he only take Coumadin and NOT Warfarin! Once we went back to Coumedin he has been good ever since and that’s been at least 15 years now!!!

  9. This is unbelieveable i ve been on coumadin 22 years i have aortic valve and mitral valve replacement can t take generic all over the place very dangerous DR. said no generic ever should be a law against it.And just what i don t need getting upset .

  10. My husband has taken Coumadin for 20 yrs, Dr gave him generic warfarin at first and he had constant pain and body aches. Then was switched to Coumadin and no pain, it worked great with little INR variation. We are very disappointed to hear he will not have access to his med that has saved his life. Is this due to covid-19? Is there any pharmaceutical company that will pick up the manufacturing of coumidin going forward. From what I read,the newer blood thinners appear to be more hazardous to ones health.

  11. It is so sad that we are being placed in a dangerous position because warfarin is a dangerous drug for me because it makes my mouth and nose bleeds. COUMADIN has worked for me for 10 years 5 months and now manufacturer wants to stop making this medication. I had to fight to get my insurance to provide for COUMADIN and now no more. I am a US Army Disabled soldier that was stationed on a very toxic military base (Ft. McClellan, Alabama) and we had mystery illnesses for 28 years. February 3, 2010, I was hospitalized with deadly blood clots in the arteries and both of my legs had to be cut open from ankle to thigh. My surgeon came a hair of amputating both of my legs but Thank God, Jesus showed up and showed out. They found a tumor camouflaged like my organs and removed that and the woman with the issue of blood was no more. I was in the hospital for 38 days. When I arrived at the hospital walking and talking; my blood count was a 3 and I didn’t have enough oxygen to circulate through my entire body. I was in surgery for 13 1/2 hours. My doctor said if I hadn’t shown up at the hospital, I would have surely died within that night. I haven’t had no issues being on BRAND COUMADIN and now it is gone like that. I have been calling every pharmacy here in Los Angeles, CA trying to get prescriptions filled. So what did the manufacturer do with all those extra COUMADIN Pills that we all need? I am contacting them in the morning to find out and if they have any on hand, I am asking them to fill my prescriptions until my vascular doctor finds something else that works and don’t have serious complications. I am praying for all. God Bless!

  12. I’m devastated with the news. Like many of you, Coumadin has provided stable INR’s for almost 26 years (as compared to generic Wafarin). I absolute do NOT want the generic. The newer anticoagulants are not suitable for me, because the majority of them contain an inactive ingredient I’m deathly allergic to. The remaining one is supposedly dangerous. Discontinuing Coumadin is like a death sentence!

    • My God yes. I felt terrible like sand running thru my veins. I gained 35 lbs in a very short time that I have been blessed with for years. I also have factor v blood. Warfarin is not the same as Coumadin. Now with it’s discontinuation what do we do? I am looking at jantoven but it has the same dyes as warfarin. I was looking at the 10 mg that has no dye. This may be a possibility to cut the pill. Checking on this now.

  13. I have been taking coumadin for many years. Initially my hematologist put me on Warfarin but i was always dizzy. Somehow he knew to switch me to Coumadin and the dizziness totally went away. Several times I tried to switch back to warfarin because it is much cheaper but the dizziness always came back. As I looked into this more, I found out that Coumadin is made from natural ingredients but warfarin is made from synthetic ingredients. Perhaps it was the synthetic ingredients that made me dizzy. It is terrible that coumadin is no longer being manufactured.

  14. This is August 2020. I phoned in for a refill of coumadin which I have been taking since 2005. Now I find out it is discontinued. I have a genetic disposition to blood clotting and DVTs. I have been hospitalized twice. Warfarin does not work for me. The drug company is abandoning many people who need this drug to stay alive. Now I am really scared.

  15. My name is Ron, I was born with Aortic Stenosis, I have been on coumadin since since 1980 after my 2nd Open Heart surgery, my 3rd Open Heart surgery was done in 1992, I have had my Aortic Valve replaced twice. I was told by my Pharmacist that coumadin was no longer available, My heart depends on this. I did try the generic brand and my test results were all over the place my doctor asked me if I was taking the correct dosage, I said yes but not coumadin, I was taking Warfarin, he told me to go back on coumadin do to my condition. So what do I do now ?

  16. I worked for heart Drs people who used warfarin were hard to get the INR stable meaning more blood test to see where their level were. Some were to low and some to high.

  17. I have been on coumadin for over 30 years. I have Factor V along with an artificial aortic valve.
    I had 3 emergency surgeries due to Warfarin in the beginning. This first time I had to receive last rites from the priest. I truly do not want to go thru or have my family go thru that again.
    How can they just discontinue a lifesaving and life sustaining medication without a Plan B?
    I have already told my son that if I bleed out start the class action suite again them.
    I am so scared for my life, this is ridiculous.

  18. I have been on Coumadin for 40 years I tryied going on warfarin many times but always had problems l had a greenfield filter inserted into my Vienna cava 40 years ago l am worried about bleeding out also have factor 5 laden

  19. Mylan Health in Australia, and Zentiva in Turkey currently manufacture Coumadin. I was told that Aspen Pharma sold the rights to Mylan. I don’t know how Zentiva got the rights.

  20. Yep, I’ve been on Coumadin since 1989 with a metal aortic valve and only when I was in rehap for replacement of a mitral valve, was I given warafin which the inr tests started moving up and down like mad…. the mitral valve is a pig valve so coumadin is not necessary. My cardio guy just prescribed Jantoven and I will start using it in about 2 months… thank God I stockpiled some Coumadin around the time they discontinued it… source was Northwest Pharmacy in Canada… they only said it was now not available, but no reason… I assumed it was to return after Covid…. Alas, no, that is why Jantoven was written by my cardio last week…. We all need to gang up on Bristol Meyers and petition mightily!

  21. I have been on Coumadin since 1999. Besides the initial problem of not being able to get INR stabile with Warfarin, I have serious side effects with all generics. I had mitral valve replacement. I just found out I can’t get my Coumadin. I’m terrified. Can’t we get help getting it from Sigma Pharma in New Zealand who bought it from Bristol Myers? How many will have to die to get a lawsuit against Bristol Myers or whoever is responsible for letting this happen.

  22. My husband has been on coumadin for seven years after a stroke. At first they had him on warfarin and he wasn’t doing well. Now we have to figure out what he can take to keep him from having another stroke. It would have been nice if they had given us some notice so we could have bought enough to last until we knew what was going to work. I think this decision has something to do with China. Why was our medicine being manufactured in China? Before the Covid-19, I was taking my husband in every 3 weeks to get tested and he was doing well. Now I am having a hard time getting him to the doctor’s. I was confident that he was ok using coumadin but now I don’t know what will happen.

  23. I have been taking warfarin for over 15 years, i’ve had 5 deep vein thrombosis that turned into pulmonary embolism, suffered suffocation 4 times, 1st at age 24, 2nd at age 30, 2 episodes at age 35, never knew i had Factor 5 Leiden until a month ago, explains it all now. Have had blood inr s inconsistent for so long, have bad sweats, diarrhea at times cheese helps a lot. Other medication’s offset the diarrhea too. It’s all been a nightmare life for me. So Tired of It

  24. got switched from warfarin to Jantovan on 7/15/20 my hair is starting to fall out first a few strands and has gone to root hair!I have been on warfarin since 2013 and have never experienced this at all.I read how generic is altered in part? this is unforgivable if their manufacturing is different than warfarin! people depend and trust our pharmacy drugs and the pharmacist to inform you of switch. are they purchasing inferior dangerous drugs for more money now? would like to know if anyone else is.or has experienced this much hair loss since starting Jantovan?

  25. you better post this comment! dont tell me it is not being published! I will copy,paste and send over the entire internet!including facebook!!

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